Absorption & Bioavailability Enhancer
Antares Vitamin E TPGS demonstrates utility as an absorption & bioavailability enhancer of lipid and poorly soluble compounds especially in conditions of malabsorption by three major mechanisms:
- Emulsification of lipid compounds and solubilization of poorly soluble compounds
- Formation of micelles and micelle-like particles in oil in water emulsions that create a large total surface area of dispersed oil which facilitates absorption
- Modulation of efflux pump activity by inhibition of the P-glycoprotein (P-gp) which is It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs
The efficacy of vitamin E TPGS as an absorption & bioavailability enhancer has been demonstrated in cell culture, animal and major human clinical studies.
If you need additional assistance regarding the use of Antares Vitamin E TPGS in your specific application, please Contact Us.
For basic handling and use guidelines for Antares Vitamin E TPGS, see How To Use TPGS.
Download Safety Data Sheet, Product Data Sheet and additional product documentation from our Documentation page.