CHEMICAL PROPERTIES OF VITAMIN E TPGS
Antares Vitamin E TPGS is the polyethylene glycol 1000 ester of d-α-tocopheryl succinate. It is chemically stable to heat, oxygen and light.
Chemical Name - d-α-tocopheryl polyethylene glycol 1000 succinate
Synonyms & Acronyms - Vitamin E TPGS or TPGS Tocophersolan (International Nomenclature of Cosmetic Ingredients – INCI and United States Adopted Names - USAN). INCI VITAMIN E.
CAS Number - 9002-96-4
Vitamin E TPGS Molecular Weight - 1513 (approximately)
d-α-tocopherol - 25% minimum weight basis
Acid Value - Not more than 0.27 ml/g
PHYSICAL PROPERTIES OF TPGS
Antares Vitamin E TPGS is a white to light tan water-soluble waxy solid with low melting point.
Physical Form - Waxy solid
Color - White to light tan (as solid)
Gardner Color - Less than 10 (generally less than 5)
Specific Gravity - 1.06 at 45 °C (approximate)
Melting Point - 38 °C (approximate), range 37-41 °C
Solubility In Water - Soluble in water at 20 wt %
Specific Rotation [α] - Not less than +24°
AMPHIPHILIC (SURFACE-ACTIVE) PROPERTIES
Antares Vitamin E TPGS has amphiphilic properties with each molecule consisting of polar hydrophilic (polyethylene glycol) and non-polar lipophilic (phytyl chain of d-α-tocopherol) moieties.
HLB (Hydrophile Lipophile Balance) - 13 (approximate)
CMC (Critical Micelle Concentration) - 0.02 weight %
Particle Size - Reported particle size diameter ranged from less than 1 and up to several microns for stable liquid emulsions